The Answer to How Breast Cancer Invades Bone
By Melissa Weber
Researchers recently solved the mystery of how breast cancer takes root in the bone. Now, the discovery has led to an experimental drug for breast cancer that has spread to the bone.
Kang and his lab team are now working with drug maker Amgen to test an experimental monoclonal antibody (a man-made protein) that blocks Jagged1 in mice.
The research out of Princeton University had me giddy with relief and excitement. "The hope is that with more options, more combined agents, we can effectively control bone metastasis and hopefully treat it as a chronic condition,” according to Yibin Kang, PhD. Hallelujah! And then I read the last sentence. Mice--they are still working on mice. It hasn't even proceeded to the testing on humans; an annoyingly long and difficult process that we know takes more time and more money--always, the money factor. Slowly slowly the wheels turn on metastatic cancer research and patiently (and hopefully) the mets clan awaits their discovery.
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